25% Vitamin C + Glutathione Clinical Serum
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Paula's Choice 25% Vitamin C + Glutathione Clinical Serum is the brand's clinical-strength answer to dark spots and dullness: a highly stable 25% vitamin C in a light, hydrating cream texture, paired...
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Paula's Choice 25% Vitamin C + Glutathione Clinical Serum is the brand's clinical-strength answer to dark spots and dullness: a highly stable 25% vitamin C in a light, hydrating cream texture, paired with glutathione to keep the vitamin C working. Paula's Choice positions it as delivering professional-level brightening without the sting.
What it actually does
- Targets uneven tone at full strength. 25% vitamin C works on discoloration, dark spots and overall radiance — one of the highest concentrations available in a leave-on serum.
- Keeps the vitamin C charged. Glutathione recharges vitamin C and amplifies the skin's own defenses, per the brand.
- Defends against the triggers. Ergothioneine supports the skin's natural antioxidants, and the brand's patented GAP technology is said to reduce the oxidative and pollution stress that drives discoloration in the first place.
- Gentle by design. Paula's Choice states this expert formulation delivers clinical-level vitamin C with zero irritation.
- Brand-reported study. In an independent 8-week clinical study of 32 subjects cited by the brand, 94% showed visibly improved discolorations and 91% had brighter-looking skin, with proven improvement in tone, radiance, firmness and elasticity.
- Formulation notes. Vegan, gluten-free and cruelty-free; free of parabens, sulfates (SLS/SLES), mineral oil, hydroquinone and formaldehyde releasers.
How to use
- For best results, use both morning and evening.
- Apply after cleansing, toning and exfoliating.
- Spread an even layer over face and neck, or spot-treat stubborn areas.
- In the daytime, always finish with SPF 30+.
Is it right for you?
Yes, if…
- Dark spots, dullness or loss of firmness are your top concerns
- Your skin is normal, dry, combination or oily — all four are listed by the brand
- Lower-strength vitamin C hasn't moved the needle for you
Think twice if…
- You're brand new to vitamin C — this is a premium, clinical-strength product and a big first investment
- You won't commit to daily SPF — brightening work undone by sun exposure is money wasted
Questions
Won't 25% vitamin C irritate my skin?
Paula's Choice says no — the formula was engineered specifically to deliver this strength without irritation, with glutathione and GAP technology soothing as it works. As with any potent active, introduce it gradually if your skin is reactive.
Morning or night?
The brand recommends both, after cleansing, toning and exfoliating. If you use it in the morning, SPF 30+ on top is essential.
How long does delivery take?
Delivery takes 3 to 21 working days, depending on availability. In-stock items arrive at the shorter end of that range; items we order in for you take longer.
How can I pay?
Credit card, debit card, Instapay and mobile wallets — no cash on delivery.
What is the return policy?
Returns are accepted for defective, damaged or expired items only, reported within 1 day of delivery. Once confirmed, we refund to the original payment method within 15–30 days.
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